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We are specialists in permanent and contract roles globally, varying from hybrid and remote to office based. The perfect role for you is out there, and our team will support you every step of the way.

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Jobs.

Senior Bioinformatics Scientist
Location
Redwood City, San Francisco, California, United States
Salary
$$180,000 - Per Annum
Job Title: Senior Bioinformatics Scientist Job Type: Permanent Salary: $170,000–$190,000 USD per year + bonus Role Location: San Francisco, CA (hybrid role) Visa Requirements: No sponsorship provided. The Company: Our client is an emerging leader within biotechnology, headquartered in the vibrant tech hub of San Francisco, California. Their mission is to empower scientists worldwide by accelerating biotech research through innovative DNA sequencing and analysis tools. Every day, thousands of innovators—including Nobel Prize winners, biotech startups, and research labs—rely on their solutions to drive world-changing discoveries in healthcare, sustainability, and beyond. In 2024, they saved researchers 2 million hours, transforming their productivity. Join their dynamic, collaborative team to shape the future of science. Role and Responsibilities: As a Senior Bioinformatics Scientist, you’ll lead the charge in building cutting-edge bioinformatics workflows that power faster, smarter science. Collaborating with a passionate team of scientists, bioinformaticians, and software engineers, you’ll drive innovation and mentor others in a creative, high-impact environment. Your key responsibilities include: Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments. Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions. Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs. Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights. Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration. Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients. Job Requirements: Education and Experience: PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines. Required Qualifications: Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools. Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments. Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing. Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda). Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows. Expertise in Git/GitHub and Linux shell scripting for version control and automation. Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit). Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing. Strong communication skills and ability to write clean, maintainable, production-ready code. Preferred Qualifications: Experience with compiled languages (C++, Rust) for performant software development. 1+ year of molecular biology wet lab experience. Demonstrated ability to develop novel bioinformatics algorithms. Strong interest in creating intuitive data visualizations for scientific insights.   Benefits: Competitive Compensation: Highly competitive remuneration. Generous Time Off: 4 weeks paid time off + 10 paid holidays. Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage. Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership. Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability. Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers. Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth.
SVP of Infrastructure & Cloud Operations
Location
US Remote, United States
Salary
$300,000 - $325,000 - Per Annum
Job title: VP of Infrastructure & Cloud Operations Job type: Permanent Bsse salary: $300,000 - $325,000 + bonus Role Location: Remote, US or Canada Visa requirements: Full Work Authorization required – US or Canada The company: Our client is a global game monetisation and payments platform, headquartered in Los Angeles with offices across Berlin, Seoul, and beyond. They partner with some of the biggest names in gaming and their platform spans over 200 geographies, supporting more than 700 payment methods in 130+ currencies. With a team of approximately 1,500 people distributed across seven countries — including Malaysia, Serbia, Azerbaijan, Canada, China, and the US — they are a truly global business at the forefront of the gaming economy. They are privately held and in a strong phase of growth, offering the successful candidate the opportunity to make a company-wide impact at scale. Role and responsibilities: Our client is seeking an experienced and visionary Vice President (or SVP) of Infrastructure and Cloud Operations to lead the strategic evolution and operational excellence of their global infrastructure. This is a senior leadership role reporting directly into the executive team, responsible for managing, optimising, and delivering both private and public cloud environments that power all of their SaaS services — ensuring resiliency, scalability, availability, and security across their platforms. Key responsibilities include: Define and execute the vision, mission, and strategic roadmap for global infrastructure and operations, aligned with business priorities and technology goals Build and scale high-performing teams across DevOps, SRE, Networking, and Database disciplines Oversee global infrastructure operations across multiple time zones and cultural environments Manage hybrid and multi-cloud environments (GCP preferred), including compute, storage, network, and security Develop and implement robust automation strategies using AI/ML to reduce toil, accelerate issue resolution, and improve system reliability Lead initiatives in observability, CI/CD security, and proactive incident prevention Ensure infrastructure is secure, compliant, and resilient, with robust business continuity and disaster recovery practices Partner with internal stakeholders across Product, Engineering, and Security to enable product velocity and stability Own the hiring, mentoring, and development of global infrastructure teams with a focus on continuous improvement Develop and manage the infrastructure budget, focusing on cost optimisation and resource forecasting Serve as a key advisor to the CTO, contributing to broader technology strategy and executive-level planning Lead vendor and service provider relationships, including SLA enforcement, performance reviews, and contract alignment Job requirements: Essential:   Minimum 10 years of experience leading infrastructure and operations across both private and public cloud platforms — public-only experience will not be considered Strong GCP experience; familiarity with multi-cloud environments essential Deep expertise in SLA and SLO management — the team is measured on availability, stability, and performance Proven leadership of DevOps, SRE, Networking, and Database Management functions with direct cross-disciplinary team responsibility Demonstrated experience reporting directly to a CTO or CIO Strong background in AI-powered automation, with hands-on experience implementing intelligent systems for monitoring, alerting, and incident resolution Experience managing and developing global, internationally distributed teams across different time zones and cultures Flexibility to work across time zones — their teams span up to 15 hours of difference (Malaysia, China, North America) Willingness to travel to international office locations, including Kuala Lumpur and/or Baku Excellent communication skills with the ability to influence at all levels including executive stakeholders A hands-on leadership style — comfortable operating at a strategic level but able to roll up their sleeves and get into the detail when required Nice to have:   Gaming or SaaS industry background Experience with observability tools such as Datadog, Prometheus, or similar Exposure to regulatory environments including SOC 2, ISO 27001, and GDPR Track record of driving digital transformation and infrastructure modernisation initiatives Experience scaling platforms to meet rapidly growing business demands Benefits:   100% company-paid medical, dental, and vision plans Unlimited flexible time off Personalised career roadmap and professional development investment High-impact, company-wide scope with genuine leadership visibility A collaborative, globally diverse team culture with a strong focus on job satisfaction and growth Accessibility Statement: Read and apply for this role in the way that works for you by using our Recite Me assistive technology tool. Click the circle at the bottom right side of the screen and select your preferences.     We make an active choice to be inclusive towards everyone every day.? Please let us know if you require any accessibility adjustments through the application or interview process.     Our Commitment to Diversity, Equity, and Inclusion: Signify’s mission is to empower every person, regardless of their background or?circumstances, with an equitable chance to achieve the careers?they deserve. Building a diverse future, one placement at a?time.   Check out our DE&I page here  
Senior Software Engineer
Location
Boston, Boston
Salary
$150000-225000 - Per Annum
Job title: Senior Software Engineer Job type: Permanent Salary: $150K – $225K + Equity  Role Location: Boston, United States The Company: We’re partnering with a well-funded, fast-scaling healthtech startup reinventing musculoskeletal care using proprietary AI and 3D-printing technology. The business has developed a web-based, sensor-free AI vision platform that transforms a 30-second scan into a clinically approved, precision-manufactured medical device. Already trusted by Fortune 50 employers, major health systems, and national manufacturers, the platform is expanding access to preventative care for hundreds of thousands of Americans. Fresh off a stealth funding round led by top-tier VCs, the company is: Growing 10x year-over-year Profitable month over month Scaling rapidly toward $100M ARR Operating with a high-ownership, execution-first culture out of Boston This is a rare opportunity to join at a true inflection point - early enough to shape the company, late enough to have real traction. Role and Responsibilities:  We’re hiring one of the founding engineers to help build and scale the core systems behind an AI-driven healthcare platform. You’ll have real ownership from day one, with a clear path to leading engineering as the company grows. You’ll influence architecture, technical direction, and engineering culture - while working on technology that measurably improves patient outcomes. Job Requirements: Strong experience with TypeScript and AWS, including infrastructure and architectural decision-making Proven experience building and scaling backend systems for real-time or AI-enabled applications Deep understanding of API design and developer-facing platforms Experience optimizing data pipelines and system performance at scale Strong fundamentals in security, reliability, and fault-tolerant system design Product-focused: You think deeply about user impact Ownership-driven: You want responsibility, not hand-holding Clear communicator: You can challenge ideas and collaborate effectively Bias to action: You move fast and ship often Mission-motivated: You want your work to change lives, not just metrics Build technology that helps people move without pain Join early enough to shape architecture, culture, and leadership Operate in a no-bureaucracy, high-trust environment Receive meaningful equity in a rapidly scaling, VC-backed healthtech company Clear runway to Head of Engineering as the business grows Accessibility Statement: Read and apply for this role in the way that works for you by using our Recite Me assistive technology tool. Click the circle at the bottom right side of the screen and select your preferences. We make an active choice to be inclusive towards everyone every day.? Please let us know if you require any accessibility adjustments through the application or interview process. Our Commitment to Diversity, Equity, and Inclusion: Signify’s mission is to empower every person, regardless of their background or?circumstances, with an equitable chance to achieve the careers?they deserve. Building a diverse future, one placement at a?time. Check out our DE&I page here
Freelance Full-Stack Engineer
Location
Europe, United States
Job Title: Senior Full Stack Engineer Job Type: Contract Contract Length: Initial 12 months Rate: €350 - €380 per day Role Location: Remote (Europe) The Company: A leading European technology company is seeking an experienced Senior Full Stack Engineer to support the development of a scalable digital platform used by businesses across multiple markets. The organisation operates internationally and is focused on delivering high-quality, customer-centric solutions. Role and Responsibilities: Design, build, and maintain full stack applications using TypeScript, Node.js, and modern frontend frameworks (Vue.js preferred). Develop and scale microservices with a focus on performance, reliability, and maintainability. Build responsive, user-friendly web applications and optimise frontend performance. Implement Infrastructure as Code (Terraform or Pulumi) and support cloud-native deployments. Manage and improve cloud infrastructure, primarily within GCP and Kubernetes environments. Create and maintain CI/CD pipelines using modern DevOps tooling. Monitor application health, troubleshoot issues, and improve system observability. Collaborate closely with product, design, and engineering teams to deliver high-quality solutions. Mentor engineers and contribute to technical best practices. Job Requirements: 6+ years of full stack software engineering experience. Strong expertise in TypeScript and Node.js. Commercial experience with Vue.js or similar frameworks such as React or Angular. Experience building microservices and working with SQL and NoSQL databases. Strong knowledge of cloud technologies, particularly GCP, Kubernetes, and containerised applications. Experience with Infrastructure as Code tools such as Terraform or Pulumi. Familiarity with CI/CD tools including GitHub Actions, CircleCI, or ArgoCD. Experience with testing frameworks such as Jest or Cypress. Strong communication and stakeholder management skills. Previous experience within fintech, payments, or highly regulated environments is advantageous. Accessibility Statement: We make an active choice to be inclusive towards everyone every day. Please let us know if you require any accessibility adjustments throughout the application or interview process. Our Commitment to Diversity, Equity, and Inclusion: Our mission is to empower every person, regardless of their background or circumstances, with an equitable opportunity to achieve the career they deserve. We are committed to building diverse and inclusive teams and welcome applications from all qualified candidates.
Principal Python Engineer
Location
London, London, United Kingdom
Salary
££135000-145000 + bonus - Per Annum
Principal Python Engineer, London, Europe's Largest Equities Exchange   We are working exclusively with one of the world's largest exchange operators on a Principal Python Engineer hire in London. This is a senior individual contributor role within a small, highly skilled engineering team building and expanding the data pipeline and event streaming infrastructure that powers the largest equities exchange in Europe.   The Role   You will lead complex engineering projects end to end, working closely with business development and sales teams to deliver new products and features, and mentoring engineers across Europe and the US. The team takes software craftsmanship seriously — testable, maintainable code, pair programming and TDD are core to how they work.   Tech Stack   Expert Python, advanced SQL, deep Linux knowledge PostgreSQL, Snowflake Apache Kafka, Apache Airflow Django, Flask or FastAPI TDD, BDD, pair programming Java familiarity a plus   What They Are Looking For   Principal or Staff level Python engineer with strong leadership skills Degree in Computer Science or related field preferred Financial markets experience a strong plus — market data, order management, algorithmic trading or financial systems integration Someone who takes genuine pride in code quality and engineering standards   The Package   Competitive salary and incentive compensation Private medical including dental, private GP service, life insurance 7% pension contribution, no employee contribution required 25 days holiday rising to 30, complimentary lunch daily 4 days in office, London  
Sr. Front End Rails Engineer
Location
Plano, United States
Job title: Senior Front End Rails Engineer Job type: Contract  Contract Length: 12-Month Contract (Ongoing) Rate: $70 - $85 per hour Role Location: US Remote The company:  A fast-growing AI-native learning platform helping organizations train employees, customers, and partners at scale. Unlike competitors who bolt AI onto legacy systems, this platform was built AI-first from the ground up — with a natural-language agentic interface connecting content creation, administration, delivery, personalization, and analytics in one unified system. They help companies launch training in minutes, not months, and are actively redefining the LMS industry Role and Responsibilities: As a Senior Front End Rails Engineer, you will architect and build core systems that power the platform at scale. You'll own complex technical challenges, drive design decisions, and set a high bar for code quality, performance, and reliability. You'll also mentor engineers, influence best practices, and partner closely with cross-functional teams to deliver impactful software.  Job Requirements:   7+ years of professional software engineering experience in scalable, high-performance production environments Strong proficiency in Ruby on Rails, JavaScript, and at least one modern frontend framework (React, Vue, or Angular) Deep expertise in OOP principles and system architecture Hands-on experience with cloud platforms (AWS, Azure, or GCP) and distributed systems Demonstrated technical leadership — mentoring engineers, facilitating alignment, contributing to sound technical decision-making Strong communicator, able to articulate technical concepts clearly to cross-functional stakeholders   Accessibility Statement:?  We make an active choice to be inclusive towards everyone every day.? Please let us know if you require any accessibility adjustments through the application or interview process.??  ?  Our Commitment to Diversity, Equity, and Inclusion:  Signify’s mission is to empower every person, regardless of their background or?circumstances, with an equitable chance to achieve the careers?they deserve. Building a diverse future, one placement at a?time.??  Check out our DE&I page here    ? 
Sr. Software Engineer - TypeScript, Next.js
Location
New York City, United States, United States
Job title: Sr. Software Engineer Job type: Contract Contract Length: 6-months Rate: $30 - $40 per hour Role Location: Remote - Latam The Company: A fast-paced, product-led engineering team building a mission-critical collaborative editing platform used by professional writers across live television, AAA video game production, and soon film. Think Google Docs, but purpose-built for the entertainment industry, with a robust API that acts as infrastructure for entire production teams. Role and Responsibilities:  Own end-to-end engineering across front end and back end - most work centers on complex front-end UX interaction and rendering Participate in Infrastructure as Code development and optimization using Terraform and AWS Contribute to team culture through clear communication, closing the loop on decisions, and collaborating effectively with both technical and non-technical teammates Participate in incident response and operational support — the team owns its own ops and handles rare incidents directly Job Requirements: 7+ years of hands-on software engineering experience Mastery of React/Next.js and TypeScript with deep experience in complex, interactive front-end development beyond standard web applications Experience with real-time collaboration tools or low-latency distributed system challenges; understanding of persistent data structures Strong communication skills and high EQ - able to work closely in a small, agile team and collaborate effectively with non-technical stakeholders Familiarity with back-end frameworks: NestJS, Prisma, Node.js Comfortable working with Postgres, Terraform, and AWS Experience with CI/CD pipelines and a no-console-changes discipline Experience with Stripe or Okta Accessibility Statement:?  We make an active choice to be inclusive towards everyone every day.? Please let us know if you require any accessibility adjustments through the application or interview process.??  Our Commitment to Diversity, Equity, and Inclusion:  Signify’s mission is to empower every person, regardless of their background or?circumstances, with an equitable chance to achieve the careers?they deserve. Building a diverse future, one placement at a?time.??  Check out our DE&I page here    ?   
SRE Engineering Manager
Location
London, London, United Kingdom
Salary
££120000-130000 + bonus - Per Annum
Senior SRE Manager, London, Global Exchange Operator London based, 4 days in office   We are working exclusively with one of the world's largest exchange operators, a business that sits at the heart of global financial markets across equities, options, futures and FX. They are looking for a Senior SRE Manager to be based in London, leading platform reliability across their European operations and global trading hours coverage.   The Role This is a senior leadership position sitting at the centre of a follow-the-sun support model. You will have direct oversight of SRE teams across European and APAC time zones, owning platform availability, incident response and operational excellence for some of the world's most critical low latency trading infrastructure. Alongside the people leadership element, you will be technically hands-on, troubleshooting complex production issues, driving automation and contributing directly to platform performance and capacity planning.   Tech Stack Low latency, bare-metal trading platforms bare metal Linux systems only (no cloud or kubernetes) UNIX shell, SQL, Python, C++ TCP/IP and Multicast networking   What They Are Looking For Proven SRE or technical operations leadership in financial markets or similarly critical infrastructure Strong understanding of US and European market structure, equities, options or futures Experience leading distributed, globally dispersed teams Excellent communicator, able to bridge technical and business stakeholders across time zones Background in software engineering or systems, network and database administration
Senior Backend Software Engineer — Python
Location
Boston, Mexico
Job title: Senior Backend Software Engineer — Python Job type: Contract Contract Length: 12 Months Rate: $35 — $45 per hour Role Location: Monterrey, MX | Hybrid The company: A fast-growing technology company building the infrastructure that powers a modern, regulated digital entertainment platform. Their proprietary engine enables partners to launch fully customized, legally compliant products that combine real-time social interactions, predictive gameplay, and entertainment in one unified experience — driving engagement, retention, and revenue at scale. This is a high-growth environment where backend engineers own critical systems, work across compliance-heavy domains, and directly influence the technical direction of a platform used by operators globally.   Role and Responsibilities: Design & Develop Backend Systems — Build scalable, resilient APIs and backend components supporting web, mobile, and third-party integrations Optimize Performance, Security & Compliance — Enhance system performance, implement security best practices, and ensure adherence to AML, KYC, data privacy, and relevant regulatory frameworks Data Infrastructure & Analytics — Develop and maintain data pipelines for analytics, fraud detection, geolocation, and regulatory reporting Technical Ownership & Collaboration — Partner with product, security, compliance, and data teams to translate requirements into effective technical solutions Operational Excellence — Participate in incident response, monitoring, and root cause analysis to ensure system stability and security Mentorship & Innovation — Share knowledge with team members, promote best practices, and explore emerging technologies in fintech, AI fraud detection, and regulated digital platforms Job Requirements: Proven experience designing, building, and scaling high-performance backend systems Strong expertise in Python for backend development, automation, and data processing Proficiency in API development, CI/CD processes, and infrastructure automation Experience in data pipeline architecture, analytics, and geolocation-based access controls Ability to mentor junior engineers and contribute to architectural decisions Familiarity with security and compliance frameworks (AML, KYC, data privacy) and performance tuning Excellent collaboration skills across cross-functional, globally distributed teams Accessibility Statement:?  We make an active choice to be inclusive towards everyone every day.? Please let us know if you require any accessibility adjustments through the application or interview process.??    Our Commitment to Diversity, Equity, and Inclusion:  Signify’s mission is to empower every person, regardless of their background or?circumstances, with an equitable chance to achieve the careers?they deserve. Building a diverse future, one placement at a?time.??  Check out our DE&I page here    ? 
Cengiz - LinkedIn testimonial
Don’t just take our word for it, listen what the community have to say...

Stephano Paraskeva,
Full Stack Developer
Euan Testimonial - Anonymous
Don’t just take our word for it, listen what the community have to say...

Euan was great to work with during my recent move to a new role. He really moved things along to meet a tight timeline and made sure I landed the salary I was aiming for. I really appreciated his transparency and how he handled the negotiation. I would highly recommend working with him!

,
Ike - LinkedIn Testimonial
Don’t just take our word for it, listen what the community have to say...

Dominika Malinowska,
Head of Data Engineering
Jack Harris - LinkedIn Testimonial
Don’t just take our word for it, listen what the community have to say...

Jack reached out to me about a role he had available and supported me throughout the entire recruitment process in a truly professional and seamless way. He was consistently responsive, over-communicated expectations, and proactively stayed on top of every step to ensure nothing fell through the cracks.

Thanks to Jack’s guidance and dedication, I was able to successfully land my new role. I would highly recommend him to anyone looking for their next opportunity.

Alejandro Trotta,
Mirth/Next Gen Developer
LD
Don’t just take our word for it, listen what the community have to say...

As a Scala developer, working with Signify has been the best thing to happen to my career. Being able to work with one agency removes so much of the overhead and headache of trying to coordinate my communications with different recruiters as I narrow down my search. I always recommend my colleagues in the programming community to work with Signify, but most of them already do!

Caesars,
Senior Scala Engineer and Developer
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